First mentions of hepatoprotective activity of Shilajit may be found in treatise of Tibetan medicine, in which it is mentioned, that Shilajit helps during “liver fever”. Data which was received during vast scientific researches show that Shilajit has pronounced anti-toxic, anti-inflammatory and spasmolytic effects. It increases glycogen and protein synthesis function in the liver, positively affects glycogen metabolism.

Hepatoprotective action of Shilajit can also be associated with presence of free and released non-essential and essential amino-acids. Thus, glutamine acid in Shilajit has pronounced hepatoprotective effect. Asparaginic acid helps liver in removing residual products of drugs and chemicals from the body, it gives strength and energy to the organism. Cystine is a strong anti-oxidant and plays a huge role in regeneration of liver cells. Valine is useful for regeneration of tissue during illnesses of liver and gall bladder.

Balanced complex of mineral substances in Shilajit has wide range of biological activity. In cases of chronic problems with liver zinc and chrome are required. Magnesium regulates tone of liver's smooth muscle. So, Shilajit can be considered an additional and rather effective drug during liver treatment.